Replikins - Online eNewsroom™

Lethality of H1N1 Virus Drops to “Non-Epidemic Resting Levels” in Current Cycle - Virus’ Infectivity Remains Increased; New Faster-Developed Synthetic Replikin Vaccines Found Effective, FluForecast(R) Gives Advance Warning of Strain-Specific Outbreaks and Cessation

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Old Biological Vaccines for Emergent Diseases — Too Little, Too Late

BOSTON, Oct. 19, 2009 — There is increasing evidence that, with best intent, current biological technology cannot supply the world’s six billion humans, and animal populations, with vaccines against emerging d…

Boston Biotech Firm Reports First Rise in 76 Years of Replikin Count* of H1N1 Lethality Gene

BOSTON, June 10, 2009 — An analysis of the latest peptide genomic data for the H1N1 influenza virus indicates that the current global outbreak of H1N1 is increasing in its capacity for lethality. The new seq…

LONDON, May 4, 2009 — A synthetic peptide H1N1 vaccine is available now for testing worldwide, from Replikins Ltd. The company has developed the vaccine based on the same Replikins peptide technology which provided the surprise advance warning one year ago that the current H1N1 outbreak/pandem…

BOSTON, April 27, 2009 — Replikins Ltd. published a FluForecast(R) warning in April 7th, 2008, a year before the recent Mexico and California H1N1 cases. The company was able to state the likelihood of H1N1 outbreaks based on its patented Replikin Count(TM) genomics technology, which examines s…

BOSTON, March 20, 2009 — Replikins, Ltd. announced today that data recently published from Harvard-CDC and Scripps-Crucell in Nature(1) and Science(2) confirms the 2001 discoveries by Dr. Samuel and Elenore Bogoch of peptides in the hemagglutinin unit of influenza, which they named Replikin…

BOSTON, Nov. 12, 2008 — WHO and CDC have stated that the predictive accuracy of their annual formulations for human influenza vaccines is “suboptimal” — often correct less than 50% of the time, especially for seniors. Perhaps in part because we are not yet accurate in our predi…

BOSTON, May 19, 2008 — Replikins Ltd. has found that very high concentrations of its replikin genetic sequences are found in the trypanosomes that are the infectious agents in malaria. The levels found by the company are in fact the highest replikin concentrations observed to date in any infectio…

BOSTON, May 2, 2008 — Replikins Ltd. has found that the replikin concentration of West Nile Virus increased annually through two distinct cycles as the virus expanded in the U.S.: the first from 2000 to 2003, and the second from 2004 to 2007 (p less than 0.001). Increases in the annual number of human…

BOSTON, April 7, 2008 — Replikins Ltd. has found that the Replikin Count(TM) of the H1N1 strain of influenza virus has recently increased to 7.6 (plus/minus 1.4), its highest level since the 1918 H1N1 pandemic (p value less than 0.001). A rising Replikin Count of a particular influenza strain, ind…

BOSTON, March 11, 2008 — Replikins, Ltd. has announced development of a chemically synthesized vaccine specific to a Taura Syndrome virus structure based on its patented Replikins(TM) technology. When the vaccine was administered orally to shrimp, 91% survived a challenge by the lethal Taura…

BOSTON, Feb. 11, 2008 — Replikins Ltd. announced that the quantitative analysis of Replikin Count(TM) in the virus gene structure predicts that the current H5N1 cycle is over. Sporadic outbreaks may continue, but the rapid epidemic spread and high mortality characteristics are expected to sub…

BOSTON, Dec. 11, 2007 — Replikins Ltd. today announced its latest findings regarding the virus replikin count in human H5N1 influenza virus. The company’s software-driven analysis has found that the prevalence of these sequences has remained high in Indonesia; in addition, higher coun…

BOSTON, Dec. 6, 2007 — A gene related to rapid replication and lethality has been found to be present in, and to contain some identical protein sequences in, tobacco mosaic virus and non-small cell lung cancer. The early detection diagnostic test for cancer, the AMAS(R) test, appears to measure th…

BOSTON, AUG. 3, 2007 — Replikins LLC has discovered a new group of virus structural peptides within virus proteins, called replikins, which provide virus-specific advance quantitative warnings of rapid replication and the risk of epidemics. Replikins LLC has developed software called Repli…

BOSTON, June 8, 2007 — The results published in 2006 by Replikins, Ltd. showed that 2005-2006 FluForecast(R) virus data indicated clearly that 1) the mortality rate of human H5N1 was increasing markedly, and that 2) the first country in which this would be clinically realized would be Indonesia.…

BOSTON, May 9, 2007 — When H5N1 was thought to be quiescent in 2006, in a prospective open trial, FluForecast(R), a software program which measures virus gene proteins, predicted high human mortality H5N1 outbreaks to come2. In addition, FluForecast technology predicted that the leading count…

Key discovery may enable development of vaccines, therapeutics

BOSTON, Jan. 25, 2007 — Viruses whose genomes constantly mutate, such as the H5N1 "bird flu," are driving a race to find relatively unchanging segments of their genomes; successful identification of these segments may…

BOSTON, Dec. 28, 2006 — A common question asked at current scientific conferences is: "Where did bird flu go?"

The recent decrease in reported H5N1 human cases and bird outbreaks might indicate that the virus has become dormant. However, quantitative analysis by Replikins, Ltd. rele…

BOSTON, Nov. 6, 2006 — Replikins, Ltd. has completed a comprehensive quantitative analysis of H5N1 "bird flu" peptide sequences found in humans infected with H5N1 in the past nine years.

The data, obtained from public sources, included 1,455 complete sequences from human specimens…

BOSTON, Oct. 25, 2006 — Researchers at Replikins, Ltd.[1] have discovered that the shrimp viruses White Spot Syndrome virus (WSSV) and Taura Syndrome virus (TSV) - global lethal pathogens for shrimp - may be reservoirs for the peptide building blocks of H5N1, or bird flu virus.

The H5N1 virus rece…

Single substitution discovered in current H5N1 was also found to be present in the last two major human pandemics of 1957 (H2N2) and 1968 (H3N2)

BOSTON, June 2, 2006 — WHO and CDC spokespersons have recently announced that no significant worrisome sequence changes have been observed so far in H5N1…